- An American medical drama television series that premiered on American Broadcasting Company (ABC) as a mid-season replacement on March 27, 2005.

- Series focuses on the fictional lives of surgical interns, residents, and attendings as they gradually evolve into seasoned doctors, while trying to maintain personal lives and     relationships.

- The title is a play on Gray's Anatomy, a human anatomy textbook by Henry Gray.

- The show was originally titled Complications following the complicated medical procedures and personal lives of the cast.

- Series revolves around the title character Dr. Meredith Grey played by Ellen Pompeo.

- The series' original cast consisted of nine star billed cast members including Ellen Pompeo, Sandra Oh, Katherine Heigl, Justin Chambers, T. R. Knight, Chandra Wilson, James Pickens Jr., Isaiah Washington and Patrick Dempsey.

- On March 3, 2016, ABC renewed Grey's Anatomy for a thirteenth season, which premiered on September 22, 2016.